What is it?

Gaucher disease is a genetic condition, not something that can spread from animal to animal. It has been identified in humans and in some animals, including Southdown and Babydoll sheep.

In 2010, Gaucher disease in sheep was officially identified by scientists after examining lambs presented by an Australian Southdown breeder. Eradication of Gaucher disease in sheep is likely to be possible through widespread DNA testing and identification of carrier sheep.

Because Southdowns are one of the oldest sheep breeds and form the genetic base of many breeds, including Babydolls, it is difficult to know when the mutation first appeared or how widely it may exist. It is not known if the disorder could be more widespread and found in other breeds of sheep. ALL Babydolls have Southdown genetics.

How it affects lambs

When a lamb is affected by Gaucher disease, it is usually:

• Unable to stand at birth

• May have abnormal or leathery skin

• Sadly, these lambs do not survive and pass away shortly after birth due to low body temperature and low blood sugar

How Gaucher disease is inherited

Gaucher disease is inherited as an autosomal recessive trait:

• Sheep with two copies of the gene are affected

• Sheep with one copy are carriers and appear completely healthy

• Sheep with no copies are Gaucher free

If both parents are carriers, each lamb has:

• A 25% chance of being affected

• A 50% chance of being a carrier

• A 25% chance of being Gaucher free

Sheep described as Gaucher free by pedigree come from parents that have been DNA tested and cannot pass the gene on.

Why awareness is important

Because carrier sheep look normal, Gaucher disease can exist in a flock without anyone realising. Over time, two carriers may be bred together, leading to the loss of lambs. Understanding and managing Gaucher disease helps protect both animal welfare and breeders’ efforts.

Testing

A simple and affordable DNA test is available through Lincoln University in New Zealand, which can identify carrier animals.

Breeders who choose not to test are unlikely to know the Gaucher status of their flock.

Is testing worth it?

Absolutely, breeding healthy, happy animals is the number one aim. Testing supports:

• Healthier lambs

• Thoughtful breeding decisions

• A gradual and responsible reduction of Gaucher disease in sheep populations

When purchasing sheep, it is reasonable to ask about Gaucher status and to support breeders who are working towards tested, healthy flocks.

Gumbuya Babydoll Sheep Stud is a Gaucher free flock.